Overview:

• Introduction to molecular mechanisms of viral replication and pathogenicity
• Methods in detection and characterization of viral infections
• Engineering viruses for biotechnology purposes
• Development of viral reagents for pharmaceutical and biomedical products

Lecture Topics:

1. The variety of viruses
2. The art of detection: Viromics
3. Molecular biology of viral replication
4. Bacteriophage and their application
5. Viral pathogenesis and disease
6. Vaccines and antiviral pharmaceuticals
7. Virus engineering and gene therapeutics

Lab Topics:

1. Observation of viral infection in bacteria – T4
2. Cytopathic effect, virus replication, and gene expression – Ranavirus
3. Pseudotyping to create viral vectors and cell transduction – Lentivirus

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