BIT 482/582 Virus Biotechnology: Pathogens to Therapeutics

Overview:

• Introduction to molecular mechanisms of viral replication and pathogenicity
• Methods in detection and characterization of viral infections
• Engineering viruses for biotechnology purposes
• Development of viral reagents for pharmaceutical and biomedical products

Lecture Topics:

1. The variety of viruses (taxonomic diversity)
2. Molecular biology of viral replication
3. Viral pathogenesis and disease
4. Working with viruses: Biosafety
5. Vaccines and antiviral pharmaceuticals
6. Virus engineering and gene therapeutics
7. The art of detection: Viromics

Lab Topics:

1. Rate of Infection and MOI – Bacteriophage
2. Virus infection of tissue cultures
3. Cytopathic effect, virus replication and gene expression – Ranavirus
4. Cell transduction and exogenous gene expression – Baculovirus

Back to Courses