BIT 479/579: High-throughput Discovery

Overview:

  • Participants will learn modern high-throughput approaches that will prepare them to design, validate, and perform cutting-edge screens and experiments.

Lectures:

  1. What is high-throughput discovery science?
  2. What makes a good screen?
  3. Screens and technology.
  4. Chemical libraries and databases.
  5. Cutting-edge screening technologies.

Labs:

  1. Molecular epidemiology qPCR screen
  2. weeks 1-2
  3. Screen for small molecules that inhibit Delftia acidovorans growth
  4. weeks 3-4
  5. Screen of stressors and sugar consumption of wild yeast strains
  6. weeks 5-6
  7. In silico image anaylsis screen
  8. week 7

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