BIT 479/579: High-throughput Discovery

Overview:

  • Participants will learn modern high-throughput approaches that will prepare them to design, validate, and perform cutting-edge screens and experiments.

Lectures:

  1. What is high-throughput discovery science?
  2. What makes a good screen?
  3. Screens and technology.
  4. Chemical libraries and databases.
  5. Cutting-edge screening technologies.

Labs:

  1. Molecular epidemiology qPCR screen
    2. weeks 1-2
  2. Screen for small molecules that inhibit Delftia acidovorans growth
    3. weeks 3-4
  3. Screen of stressors and sugar consumption of wild yeast strains
    4. weeks 5-6
  4. In silico image anaylsis screen
    5. week 7

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