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“Molecular Biotechnology comprises a set of universal
laboratory skills that complement academic preparation
in disciplines impacted by the life sciences.”

DR. ROBERT M. KELLY, DIRECTOR

Molecular Biotechnology Education

The Biotechnology Program (BIT) at NC State University.

About the image: In the BIT Organoids course, students use mouse intestinal organoids to study cancer initiation. Students transfect organoids with CRISPR/Cas9 editing tools to delete the gene Apc and a second gene of interest. Apc is an important part of the Wnt pathway, and disrupted Wnt signaling is a key early change that happens in intestinal cancer. This image shows a brightfield image of a CRISPR/Cas9-editing Apc-knockout organoid that is thriving in conditions that have killed the non-knockout cells around it. Image credits: Taylor Roberts (transfection) and Ravi Appalabhotla (CRISPR knockout) in Dr. Leigh Ann Samsa’s class.

New award! Congratulations to Dr. Dums for receiving a Postdoctoral Meeting Award to present his pedagogical work on growth mindset at the ASBMB 2021 National Meeting.

New DELTA Course Design Grant:  The BIT team received a DELTA Course Design Grant to develop an online BIT 410/510 course: EASEE Enhancing Access to Science Through Equitable online Education.”

Re-designed course launched this fall: BIT 474/574: Plant Genetic Engineering

New publications: Dr. Arnab Sengupta published his research in the prestigious journal Nature Communications!

van der Stel, AX., Gordon, E.R., Sengupta, A. et al. Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling. Nat Commun 12, 5340 (2021). https://doi.org/10.1038/s41467-021-25663-8

Collaborations: BIT leads a multi-institution project to expand Molecular Biotechnology Laboratory Education Modules (MBLEMs) with five partner institutions.

Training hundreds of students from across campus…

Offering cutting-edge molecular biotechnology courses…

Mentoring versatile scientists in course-based and one-on-one research experiences

Leading innovative biotechnology education initiatives